Dr. Farrukh Aqil

University of Louisville, USA

Associate Professor

Email: [email protected]

Qualifications

2006 Ph.D., Aligarh Muslim University, India

2000 M.Sc., Aligarh Muslim University, India

1998 B.Sc., Aligarh Muslim University, India

Publications (Selected)

1. Moholkar, D.N., Kandimalla, R., Wallen, M., Yaddanapudi, K., Gupta, R. and Aqil, F. Diagnostic and Therapeutic Applications of Exosomes in Lung Cancer. Cells, 15(7), 632, 2026.  
2. Moholkar, D.N., Kandimalla, R., Jeyabalan, J., Singhal, R., Mayer, K., Klinge, C.M. and others. Exosomal cannabidiol: A promising candidate for targeted oral delivery against breast cancer. Cancer Letters, 218416, 2026.  
3. Moholkar, D.N., Kandimalla, R., Saeed, M., Arif, Y., Tyagi, N., Singhal, R. and others. Tumor-targeted Exosomal Delivery of Celastrol for Enhanced Therapeutic Efficacy in NSCLC. Theranostics, 16(10), 5125, 2026.  
4. Kandimalla, R., Aqil, F., Saxena, D., Wallen, M., Saeed, M., Moholkar, D.N. and others. Exosome-mediated antiviral testing system and identification of Punicalagins and Anthocyanidins as promising antiviral agents against SARS-CoV-2. Biomedicine & Pharmacotherapy, 196, 119111, 2026.  
5. Moholkar, D.N., Kandimalla, R., Jeyabalan, J., Gupta, R.C. and Aqil, F. Exosomal formulation of cannabidiol (CBD) inhibits lung cancer proliferation and enhances uptake and tumor targeting. Cancer Research, 85(8_Supplement_1), 1788, 2025.  
6. Kandimalla, R., Saeed, M., Gupta, R.C. and Aqil, F. Drug deliverypaper 21-s2.0-S0149763422004638-main.pdf. Health Research Alliance, 2025.  
7. Al-Balushi, R.A., Chaudhuri, A., Kandimalla, R., Haque, A., Alenezi, K.M. and others. In vitro anticancer effects of frankincense and its nanoemulsions for enhanced cancer cell targeting. Frontiers in Pharmacology, 16, 1403780, 2025.  
8. Moholkar, D.N., Kandimalla, R., Jeyabalan, J., Yan, J., Song, Z.H., Aqil, F. and others. Targeted Oral Delivery of Exosomal Formulation of Cannabidiol against Lung Cancer. Advanced Therapeutics, 2400362, 2025.  
9. Saeed, M., Alshammari, N., Saeed, A., AL-Shammary, A.A. and others. Molecular interactions of cucurbitacins A and B with anaplastic lymphoma kinase for lung cancer treatment. Journal of Biomolecular Structure and Dynamics, 42(23):13165-13173, 2024.  
10. Saeed, M., Alshaghdali, K., Moholkar, D.N., Kandimalla, R., Kausar, M.A. and Aqil, F. Camel milk-derived exosomes as novel nanocarriers for curcumin delivery in lung cancer. Biomolecules and Biomedicine, 26(1):132, 2024.  
11. Gupta, R.C. Exosomes in Cancers Therapy. MDPI, 2024.  
12. Kandimalla, R., Moholkar, D.N., Samanta, S.K., Tyagi, N., Aqil, F. and Gupta, R. Oncogene downregulation by mahanine suppresses drug-sensitive and drug-resistant lung cancer and inhibits orthotopic tumor progression. Cancers, 16(21), 3572, 2024.  
13. Welsh, J.A., Goberdhan, D.C.I., O'Driscoll, L., Buzas, E.I., Blenkiron, C. and others. Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches. Journal of Extracellular Vesicles, 13(2), e12404, 2024.  
14. Samanta, S.K., Choudhury, P., Kandimalla, R., Aqil, F., Moholkar, D.N. and others. Mahanine mediated therapeutic inhibition of estrogen receptor-α and CDK4/6 expression, decipher the chemoprevention-signaling cascade in preclinical model of breast cancer. Journal of Ethnopharmacology, 319, 117235, 2024.  
15. Moholkar, D.N., Kandimalla, R., Gupta, R.C. and Aqil, F. Advances in lipid-based carriers for cancer therapeutics: Liposomes, exosomes and hybrid exosomes. Cancer Letters, 565, 216220, 2023.  
16. Wallen, M., Aqil, F., Spencer, W. and Gupta, R.C. Exosomes as an emerging plasmid delivery vehicle for gene therapy. Pharmaceutics, 15(7), 1832, 2023.  
17. Asif, M., Aqil, F., Alasmary, F.A., Almalki, A.S., Khan, A.R. and Nasibullah, M. Lewis base-catalyzed synthesis of highly functionalized spirooxindole-pyranopyrazoles and their in vitro anticancer studies. Medicinal Chemistry Research, 32(5):1001-1015, 2023.  
18. Wallen, M., Aqil, F., Spencer, W. and Gupta, R.C. Milk/colostrum exosomes: A nanoplatform advancing delivery of cancer therapeutics. Cancer Letters, 561, 216141, 2023.  
19. Saeed, M., Shoaib, A., Kandimalla, R., Javed, S., Almatroudi, A., Gupta, R. and Aqil, F. Microbe-based therapies for colorectal cancer: Advantages and limitations. Seminars in Cancer Biology, 86:652-665, 2022.  
20. Wallen, M., Aqil, F., Kandimalla, R., Jeyabalan, J., Auwardt, S., Tyagi, N. and others. A model system for antiviral siRNA therapeutics using exosome-based delivery. Molecular Therapy Nucleic Acids, 29:691-704, 2022.  
21. Kumar, D.N., Chaudhuri, A., Aqil, F., Dehari, D., Munagala, R., Singh, S. and others. Exosomes as emerging drug delivery and diagnostic modality for breast cancer: recent advances in isolation and application. Cancers, 14(6), 1435, 2022.  
22. Aqil, F. and Gupta, R.C. Exosomes in cancer therapy. Cancers, 14(3), 500, 2022.  
23. Aqil, F., Munagala, R., Agrawal, A.K., Jeyabalan, J., Tyagi, N., Rai, S.N. and Gupta, R.C. Anthocyanidins inhibit growth and chemosensitize triple-negative breast cancer via the NF-κB signaling pathway. Cancers, 13(24), 6248, 2021.  
24. Kandimalla, R., Aqil, F., Alhakeem, S.S., Jeyabalan, J., Tyagi, N., Agrawal, A. and others. Targeted oral delivery of paclitaxel using colostrum-derived exosomes. Cancers, 13(15), 3700, 2021.

Personal Details

WoS Researcher ID: AFK-2012-2022

https://orcid.org/0000-0002-0081-7251

https://profiles.louisville.edu/farrukh.aqil

https://scholar.google.com/citations?user=OFx6FB0AAAAJ&hl=en

https://www.researchgate.net/profile/Farrukh-Aqil