Dr. Jie Chen
University
of Pennsylvania, Philadelphia, USA
Email:[email protected]
Qualifications
2016 Ph.D., The University of Hong Kong, DNA
Damage Repair and Cancer
2011 M.Sc., Capital Normal University, Cell
Biology
2008 B.Sc., Huazhong Agricultural University,
National Cultivation Base of Life Science and Technology
Publications (Selected)
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Li, X., An, L., Jin, Y., Gui, J., Lin, W., Wen, Z., ... & Chen, J. (2023). Viral infection, tumor development and host immune response. Frontiers in Cellular and Infection Microbiology, 13, 1177032.
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Chen, J., Harding, S. M., Natesan, R., Tian, L., Benci, J. L., Li, W., ... & Greenberg, R. A. (2020). Cell cycle checkpoints cooperate to suppress DNA-and RNA-associated molecular pattern recognition and anti-tumor immune responses. Cell reports, 32(9).
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Roewenstrunk, J., Di Vona, C., Chen, J., Borras, E., Dong, C., Arató, K., ... & de la Luna, S. (2019). A comprehensive proteomics-based interaction screen that links DYRK1A to RNF169 and to the DNA damage response. Scientific reports, 9(1), 6014.
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An, L., Dong, C., Li, J., Chen, J., Yuan, J., Huang, J., ... & Huen, M. S. (2018). RNF169 limits 53BP1 deposition at DSBs to stimulate single-strand annealing repair. Proceedings of the National Academy of Sciences, 115(35), E8286-E8295.
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An, L., Jiang, Y., Ng, H. H., Man, E. P., Chen, J., Khoo, U. S., ... & Huen, M. S. (2017). Dual-utility NLS drives RNF169-dependent DNA damage responses. Proceedings of the National Academy of Sciences, 114(14), E2872-E2881.
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Zhang, X., Chen, J., Wu, M., Wu, H., Arokiaraj, A. W., Wang, C., ... & Zang, J. (2013). Structural basis for role of ring finger protein RNF168 RING domain. Cell Cycle, 12(2), 312-321.
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Chen, J., Feng, W., Jiang, J., Deng, Y., & Huen, M. S. (2012). Ring finger protein RNF169 antagonizes the ubiquitin-dependent signaling cascade at sites of DNA damage. Journal of Biological Chemistry, 287(33), 27715-27722.
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Zhang, W. W., Zhang, X. J., Liu, H. X., Chen, J., Ren, Y. H., Huang, D. G., ... & Xiao, W. (2011). Cdk1 is required for the self‐renewal of mouse embryonic stem cells. Journal of cellular biochemistry, 112(3), 942-948.
Profile Details
https://www.med.upenn.edu/apps/faculty/index.php/g275/p8935031
https://scholar.google.com/citations?user=o3bztPYAAAAJ&hl=en
https://www.researchgate.net/profile/Jie-Chen-272