Dr. Nirnath Sah

Johns Hopkins School of Medicine, Baltimore, USA

Email: [email protected]; [email protected]

Qualifications

Ph.D., Indian Institute of Science, Bangalore, India

M.S., University of Calcutta, Kolkata, India

B.S., University of Calcutta, Kolkata, India

Publications (Selected)

1. Sharma, A., Sah, N., Sharma, R., Vyas, P., Liyanage, W., Kannan, S., & Kannan, R. M. (2024). Development of a novel glucose‐dendrimer based therapeutic targeting hyperexcitable neurons in neurological disorders. Bioengineering & Translational Medicine, 9(5), e10655.
2. Almodiel, D., Sah, N., Liyanage, W., Rangaramanujam, K., Kannan, S., & Santhanam, L. (2024). Macrophage Targeted Dendrimer-Tesaglitazar Therapy for Atherosclerosis. Physiology, 39(S1), 1542.
3. Khoury, E. S., Patel, R. V., O'Ferrall, C., Fowler, A., Sah, N., Sharma, A., ... & Kannan, S. (2024). Dendrimer nanotherapy targeting of glial dysfunction improves inflammation and neurobehavioral phenotype in adult female Mecp2‐heterozygous mouse model of Rett syndrome. Journal of neurochemistry, 168(5), 841-854.
4. Zhu, X., Joo, Y., Bossi, S., McDevitt, R. A., Xie, A., Wang, Y., ... & Wang, W. (2024). Tdrd3-null mice show post-transcriptional and behavioral impairments associated with neurogenesis and synaptic plasticity. Progress in neurobiology, 233, 102568.
5. Bedner, A., Vyas, P., Sah, N., Zhang, C., Uniyal, A., Smith-Hicks, C., ... & Kannan, S. (2024). 847: PAIN PERCEPTIONS IN NEURODEVELOPMENTAL DISORDERS: EVALUATION IN A MOUSE MODEL OF RETT SYNDROME. Critical Care Medicine, 52(1), S396.
6. Sah, N., Zhang, Z., Chime, A., Fowler, A., Mendez-Trendler, A., Sharma, A., ... & Kannan, S. (2023). Dendrimer-conjugated glutamate carboxypeptidase II inhibitor restores microglial changes in a rabbit model of cerebral palsy. Developmental Neuroscience, 45(5), 268-275.
7. Sharma, A., Sah, N., Sharma, R., Vyas, P., Liyanage, W., Kannan, S., & Kannan, R. M. (2024). Development of a novel glucose‐dendrimer based therapeutic targeting hyperexcitable neurons in neurological disorders. Bioengineering & Translational Medicine, 9(5), e10655.
8. Porterfield, J. E., Sharma, R., Jimenez, A. S., Sah, N., McCracken, S., Zhang, L., ... & Kannan, R. M. (2023). Small cell lung cancer: New drugs and strategies. BIOENGINEERING & TRANSLATIONAL MEDICINE, 8(3).
9. Porterfield, J. E., Sharma, R., Jimenez, A. S., Sah, N., McCracken, S., Zhang, L., ... & Kannan, R. M. (2023). Galactosylated hydroxyl‐polyamidoamine dendrimer targets hepatocytes and improves therapeutic outcomes in a severe model of acetaminophen poisoning‐induced liver failure. Bioengineering & Translational Medicine, 8(3), e10486.
10. Modi, H. R., Wang, Q., Olmstead, S. J., Khoury, E. S., Sah, N., Guo, Y., ... & Thakor, N. V. (2022). Systemic administration of dendrimer N‐acetyl cysteine improves outcomes and survival following cardiac arrest. Bioengineering & Translational Medicine, 7(1), e10259.
11. Shi, A., Khoury, E., Sah, N., Fowler, A., Liaw, K., Sharma, A., ... & Kannan, S. (2021). Characterization of microglial phagocytosis and dendrimer nanoparticle uptake in a neonatal rabbit model of cerebral palsy. Precis Nanomedicine, 4(4), 840-850.
12. Sharma, A., Sah, N., Kannan, S., & Kannan, R. M. (2021). Targeted drug delivery for maternal and perinatal health: Challenges and opportunities. Advanced drug delivery reviews, 177, 113950.
13. Joo, Y., Xue, Y., Wang, Y., McDevitt, R. A., Sah, N., Bossi, S., ... & Wang, W. (2020). Topoisomerase 3β knockout mice show transcriptional and behavioural impairments associated with neurogenesis and synaptic plasticity. Nature communications, 11(1), 3143.
14. Terreros-Roncal, J., Flor-García, M., Moreno-Jiménez, E. P., Pallas-Bazarra, N., Rábano, A., Sah, N., ... & Llorens-Martín, M. (2019). Activity-dependent reconnection of adult-born dentate granule cells in a mouse model of frontotemporal dementia. Journal of Neuroscience, 39(29), 5794-5815.
15. Shen, M., Wang, F., Li, M., Sah, N., Stockton, M. E., Tidei, J. J., ... & Zhao, X. (2019). Reduced mitochondrial fusion and Huntingtin levels contribute to impaired dendritic maturation and behavioral deficits in Fmr1-mutant mice. Nature neuroscience, 22(3), 386-400.
16. Sah, N. (2018). GABAA Receptor Mediated Phasic and Tonic Inhibition in Subicular Pyramidal Neurons (Doctoral dissertation).
17. Sah, N., Peterson, B. D., Lubejko, S. T., Vivar, C., & van Praag, H. (2017). Running reorganizes the circuitry of one-week-old adult-born hippocampal neurons. Scientific reports, 7(1), 10903.
18. Moon, H. Y., Becke, A., Berron, D., Becker, B., Sah, N., Benoni, G., ... & van Praag, H. (2016). Running-induced systemic cathepsin B secretion is associated with memory function. Cell metabolism, 24(2), 332-340.
19. Sah, N., & Sikdar, S. K. (2014). Tonic current through GABA A receptors and hyperpolarization‐activated cyclic nucleotide‐gated channels modulate resonance properties of rat subicular pyramidal neurons. European Journal of Neuroscience, 40(1), 2241-2254.
20. Sah, N., & Sikdar, S. K. (2013). Transition in subicular burst firing neurons from epileptiform activity to suppressed state by feedforward inhibition. European Journal of Neuroscience, 38(4), 2542-2556.

Profile Details

https://anesthesiology.hopkinsmedicine.org/wp-content/uploads/2022/12/ACCM-Research-Day-Book-2022.12.07.pdf

https://scholar.google.com/citations?user=WJP_ztUAAAAJ&hl=en

https://irp.nida.nih.gov/staff-members/nirnath-sah/

https://www.linkedin.com/in/nirnath-sah/