Biography

Prof. Ghulam Md Ashraf

Department of Biomedical Sciences,
College of Medicine, Gulf Medical University, Ajman, United Arab Emirates

Associate Professor


Email: [email protected], [email protected]


Qualifications

2006-2011 PhD., Biochemistry, Aligarh Muslim University, Uttar Pradesh, India

2004-2006 M.Sc., Biochemistry, Aligarh Muslim University, Uttar Pradesh, India

2001-2004 B.Sc., Biochemistry, Aligarh Muslim University, Uttar Pradesh, India


Featured Publications



  1. Alam MZ, Bagabir H, Zaher MAF, Alqurashi TMA, Alghamdi BS, Kazi M, Suhail M, Alshahrany GA, Alzahrani NA, Bakhalgi RM, Al-Thepyani M, AboTaleb HA, Aldhahri RS, Juweiriya, Tash R, Ashraf GM*. Curcumin-piperine nanoparticles mitigate cuprizone-induced cognitive impairment via antioxidant and anti-Inflammatory mechanisms. Frontiers in Nutrition (2025) 12:1633855. PMID: [Impact Factor: 5.1]
  2. Alam MZ, Bagabir HA, Zaher MAF, Alqurashi TMA, Alghamdi BS, Kazi M, El-Aziz GS, Alshahrany GA, Alzahrani NA, Bakhalgi RM, Al-Thepyani M, AboTaleb HA, Aldhahri RS, Juweiriya, Ashraf GM*. Curcumin–piperine self-nanoemulsifying delivery in Zanthoxylum rhetsa seed oil attenuates cuprizone-induced frontal cortex toxicity. Pharmaceuticals. (2025)18(10):1478. PMID: [Impact Factor: 4.8]
  3. Jiang Y, Zhou Y, Wang Y, Li Z, Ashraf GM*, Guo L. Telomerase dynamics in stem cells: unraveling the molecular nexus of cellular aging and regeneration. Ageing Research Reviews (2025) 112:102853. PMID: 40759311 [Impact Factor: 12.4]
  4. Alam MZ, Bagabir HA, Zaher MAF, Alqurashi TMA, Alghamdi BS, Kazi M, Ashraf GM*, Alshahrany GA, Alzahrani NA, Bakhalgi RM, Juweiriya, Al-Thepyani M, AboTaleb HA, Aldhahri RS, El-Aziz GSA, Al-Abbasi FA, Eibani LK, Alzahrani FJ, Khan MSA. Black seed oil-based curcumin nanoformulations ameliorated cuprizone-induced demyelination in the mouse hippocampus. Molecular Neurobiology (2025) 62(1):604-625. PMID: 38890237 [Impact Factor: 5.1]
  5. Saha P, Panda S, Holkar A, Vashishth R, Rana SS, Arumugam M, Ashraf GM*, Haque S, Ahmad F. Neuroprotection by agmatine: Possible involvement of the gut microbiome? Ageing Research Reviews (2023) 91:102056. PMID: 37673131 [Impact Factor: 13.1]
  6. Preetam S, Jonnalagadda S, Kumar L, Rath R, Chattopadhyay S, Alghamdi BS, Abuzenadah AM, Jha N, Gautam A, Malik S, Ashraf GM*. Therapeutic potential of lipid nanosystems for the treatment of Parkinson’s disease. Ageing Research Reviews (2023) 31:101965. PMID: 37268112 [Impact Factor: 13.1]
  7. Aldhahri RS, Alghamdi BS, Alzahrani NA, Bahaidrah KA, Alsufiani HM, Mansouri RA, Ashraf GM*. Biochanin A improves memory decline and brain pathology in cuprizone- induced mouse model of multiple sclerosis. Behavioral Sciences (2022) 12(3):70. PMID:35323389 [Impact Factor: 2.6]
  8. Ashraf GM*, Chatzichronis S, Alexiou A, Firdousi G, Kamal MA, Ganash M. Dietary alterations in impaired mitochondrial dynamics due to neurodegeneration. Frontiers in Aging Neuroscience (2022) 14:893018. PMID: 35898328 [Impact Factor: 5.702]
  9. Mamun AA, Uddin MS, Perveen A, Jha NK, Alghamdi BS, Jeandet P, Zhang HJ, Ashraf GM*. Inflammation-targeted nanomedicine against brain cancer: from design strategies to future developments. Seminars in Cancer Biology (2022) 86(2):101-116. PMID: 36084815. [Impact Factor: 17.012]
  10. Ashraf GM*, Alghamdi BS, Alshehri FS, Alam MZ, Tayeb HO, Tarazi FI.Empagliflozin effectively attenuates olanzapine-induced body weight gain in female Wistar rats. Frontiers in Pharmacology (2021) 12:578716. PMID: 33953666 [Impact Factor: 5.810]
  11. Ashraf GM*, Alghamdi BS, Alshehri FS, Alam MZ, Tayeb HO, Tarazi FI.Standardizing the effective correlated dosage of olanzapine and empagliflozin in female Wistar rats. Current Gene Therapy (2021) 21(1):53-59. PMID: 33183202 [Impact Factor: 4.391]
  12. Uddin MS, Mamun AA, Alghamdi BS, Tewari D, Jeandet P, Sarwar MS, Ashraf GM*. Epigenetics of glioblastoma multiforme: from molecular mechanisms to therapeutic approaches. Seminars in Cancer Biology (2021) 83:100-120. PMID: 33370605 [Impact Factor: 15.707]
  13. Ullah MF, Ahmad A, Bhat SH, Abu-Duhier FM, Barreto GE, Ashraf GM*. Impact of sex differences and gender specificity on behavioral characteristics andpathophysiology of neurodegenerative disorders. Neuroscience and Biobehavioral Reviews (2019) 102:95-105. PMID: 30959072 [Impact Factor: 8.002]




Publications (Selected)

  1. Vignesh, V., Balaji, A. N., Nagaprasad, N., Sanjay, M. R., Khan, A., Asiri, A. M., ... & Siengchin, S. (2021). Indian mallow fiber reinforced polyester composites: Mechanical and thermal properties. Journal of Materials Research and Technology, 11, 274-284.
  2. Uddin MS, Tewari D, Mamun AA, Kabir MT, Niaz K, Wahed MIW, Barreto GE, Ashraf GM*. Circadian and sleep dysfunction in Alzheimer's disease. Ageing Research Reviews (2020) 60:101046. [Impact Factor: 10.39]
  3. Pottoo FH, Tabassum N, Javed MN, Nigar S, Sharma S, Barkat MA, Harshita, Alam MS, Ansari MA, Barreto GE, Ashraf GM*. Raloxifene potentiates the effect of fluoxetine against maximal electroshock induced seizures in mice. European Journal of Pharmaceutical Science (2020) 146:105261. [Impact Factor: 3.532]
  4. Ashraf GM, Tarasov VV, Makhmutovа A, Chubarev VN, Avila-Rodriguez M, Bachurin SO, Aliev G. The possibility of an infectious etiology of Alzheimer disease. Molecular Neurobiology (2019) 56:4479-4491. [Impact Factor: 4.586]
  5. Vesga-Jiménez DJ, Hidalgo-Lanussa O, Baez-Jurado E, Echeverria V, Ashraf GM, Sahebkar A, Barreto GE. Raloxifene attenuates oxidative stress and preserves mitochondrial function in astrocytic cells upon glucose deprivation. Journal of Cellular Physiology (2019) 234(3):2051-2057. [Impact Factor: 4.522]
  6. Pottoo FH, Tabassum N, Javed MN, Nigar S, Rasheed R, Khan A, Barkat MA, Alam MS, Maqbool A, Ansari MA, Barreto GE, Ashraf GM. The synergistic effect of raloxifene, fluoxetine, and bromocriptine protects against pilocarpine-induced status epilepticus and temporal lobe epilepsy. Molecular Neurobiology (2019) 56:1233-1247. [Impact Factor: 4.586]
  7. Baez-Juradoa E, Rincón-Benavidesa MA, Hidalgo-Lanussaa O, Guio-Vegaa G, Ashraf GM, Sahebkar A, Echeverria V, Garcia-Segura LM, Barreto GE. Molecular mechanisms involved in the protective actions of Selective Estrogen Receptor Modulators in brain cells. Frontiers in Neuroendocrinology (2019) 52:44-64. [Impact Factor: 7.852]
  8. Shakil, S., Baig, M. H., Tabrez, S., Rizvi, S. M. D., Zaidi, S. K., Ashraf, G. M., ... & Chaudhary, A. G. (2019, June). Molecular and enzoinformatics perspectives of targeting Polo-like kinase 1 in cancer therapy. In Seminars in cancer biology (Vol. 56, pp. 47-55). Academic Press.
  9. Baig, M. H., Baker, A., Ashraf, G. M., & Dong, J. J. (2019). ASK1 and its role in cardiovascular and other disorders: available treatments and future prospects. Expert Review of Proteomics, 16(10), 857-870.
  10. Herrera, A. S., A. Esparza, M. D. C., Arias, P. E., Ashraf, G. M., Mosa, O. F., Fisenko, V. P., ... & Aliev, G. (2019). The role of melanin to dissociate oxygen from water to treat retinopathy of prematurity. Central Nervous System Agents in Medicinal ChemistryChemistry-Central Nervous System Agents), 19(3), 215-222.
  11. Ashraf GM*, Baeesa SS. Investigation of Gal-3 expression pattern in serum and cerebrospinal fluid of patients suffering from neurodegenerative disorders. Frontiers in Neuroscience (2018) 12:430. [Impact Factor: 3.648]
  12. Korada, S. K., Yarla, N. S., Mishra, V., Daim, M. A., Sharma, B., Gm, A., ... & Kamal, M. A. (2018). Single probiotic versus multiple probiotics-a debate on current scenario for alleviating health benefits. Current Pharmaceutical Design, 24(35), 4150-4153.
  13. Sirisha, G. V., Rachel, K. V., Zaveri, K., Yarla, N. S., Kiranmayi, P., Ganash, M., ... & Ashraf, G. M. (2018). Molecular docking and in vitro studies of soap nut trypsin inhibitor (SNTI) against phospholipase A2 isoforms in therapeutic intervention of inflammatory diseases. International journal of biological macromolecules, 114, 556-564.
  14. Korada, S. K., Yarla, N. S., Putta, S., Hanumakonda, A. S., Lakkappa, D. B., Bishayee, A., ... & Peluso, I. (2018). A critical appraisal of different food safety and quality management tools to accomplish food safety. In Food safety and preservation (pp. 1-12). Academic Press.
  15. Bilal, N., Suhail, N., Hasan, S., Ashraf, G. M., Fatima, S., Khan, H. Y., ... & Banu, N. (2017). Exacerbation of N-nitrosodiethylamine induced hepatotoxicity and DNA damage in mice exposed to chronic unpredictable stress. Frontiers in pharmacology, 8, 360.
  16. Khan MF, Ansari AH, Hameedullah M, Ahmad E, Husain FM, Zia Q, Baig U, Zaheer MR, Alam MM, Khan AM, AlOthman ZA, Ahmad I, Ashraf GM*, Aliev G. Solgel synthesis of thorn-like ZnO nanoparticles endorsing mechanical stirring effect and their antimicrobial activities: Potential role as nano-antibiotics. Scientific Reports, (2016) 6: 27689 | DOI: 10.1038/srep27689.
  17. Hasan S, Suhail N, Bilal, N., Ashraf, GM, Zaidi SK, AlNohair S, Banu N. Chronic unpredictable stress deteriorates the chemopreventive efficacy of pomegranate through oxidative stress pathway. Tumor Biology, (2016) 37, 5999–6006.
  18. Perveen A, Barreto GE, Jahan N, Wadud A, Alam MT, Ashraf GM, Aliev G. Antifertility activity of Lac (Laccifer lacca Kerr.) in female Wistar rat model. Immunology, Endocrine & Metabolic Agents in Medicinal Chemistry, (2016) 16(1), 39-48.
  19. Ashraf GM*, Chibber S, Mohammad, Zaidi SK, Tabrez S, Ahmad A, Shakil S, Mushtaq G, Baeesa SS, Kamal MA. Recent updates on the association between Alzheimer’s disease and vascular dementia. Medicinal Chemistry, (2016) 12(3), 1-12.
  20. Ashraf GM#,*, Ali A1,#, Tabrez S, Zaidi SK, Shakil S, Alam MZ, Rehan M, Aliev G. Linkage of stress with neuromuscular disorders. CNS & Neurological Disorders – Drug Targets, (2016) 15(3), 321-328.


Global Recognition

  1. 2021-Present  Top 2% Scientist Worldwide (Stanford-Plos-Elsevier)
  2. 2023-Present Biochemistry Best Scientist (Rank #1) in the United Arab Emirates
  3. 2021-Present  Expertscape World Expert (Top 0.011%) in Neurodegenerative Diseases (Rank #1 in UAE and Saudi Arabia, Rank #10 in Asia, Rank #49 in The World)
  4. 2021-Present Expertscape World Expert (top 0.02%) in Alzheimer’s Disease (Rank #1 in UAE and Saudi Arabia, Rank #9 in Asia, Rank #34 in the World)



Profile Details

Orcid: https://orcid.org/0000-0002-9820-2078
LinkedIn: https://www.linkedin.com/in/ashraf-gm-18134137b/
Scopus: https://www.scopus.com/authid/detail.uri?authorId=16444016700
Web of Science: https://www.webofscience.com/wos/author/record/H-9485-2012
Google scholar: http://scholar.google.com/citations?user=-fOCOTQAAAAJ&hl=e

SCIRP Newsletter
Copyright © 2006-2026 Scientific Research Publishing Inc. All Rights Reserved.
Top