DNA recombinases are widely used in multicellular organisms to manipulate the structure of genomes, and to control gene expression. These enzymes, derived from bacteria (bacteriophages) and fungi, catalyze directionally sensitive DNA exchange reactions between short (30–40 nucleotides) target site sequences that are specific to each recombinase. These reactions enable four basic functional modules: excision/insertion, inversion, translocation and cassette exchange, which have been used individually or combined in a wide range of configurations to control gene expression.

In the present book, ten typical literatures about recombinases published on international authoritative journals were selected to introduce the worldwide newest progress, which contains reviews or original researches on recombinases. We hope this book can demonstrate advances in recombinases as well as give references to the researchers, students and other related people.