Advances in Dysautonomia
Dysautonomia, autonomic failure, or autonomic dysfunction is a condition in which the autonomic nervous system (ANS) does not work properly. This condition may affect the functioning of the heart, bladder, intestines, sweat glands, pupils, and blood vessels. Dysautonomia has many causes, not all of which may be classified as neuropathic. A number of conditions can feature dysautonomia, such as Parkinson's disease, Long COVID, multiple system atrophy, dementia with Lewy bodies, Ehlers–Danlos syndromes, autoimmune autonomic ganglionopathy and autonomic neuropathy, HIV/AIDS, mitochondrial cytopathy, pure autonomic failure, autism, and postural orthostatic tachycardia syndrome.
In the present book, twelve typical literatures about dysautonomia published on international authoritative journals were selected to introduce the worldwide newest progress, which contains reviews or original researches on dysautonomia. We hope this book can demonstrate advances in dysautonomia as well as give references to the researchers, students and other related people.
Sample Chapter(s)
Preface (179 KB)
Components of the Book:
  • Chapter 1
    Gut microbiome dysbiosis drives metabolic dysfunction in Familial dysautonomia
  • Chapter 2
    Therapeutic manipulation of IKBKAP mis-splicing with a small molecule to cure familial dysautonomia
  • Chapter 3
    Norepinephrine transporter defects lead to sympathetic hyperactivity in Familial Dysautonomia models
  • Chapter 4
    Mismatch between subjective and objective dysautonomia
  • Chapter 5
    Clinical characterization of dysautonomia in long COVID-19 patients
  • Chapter 6
    Dysautonomia and REM sleep behavior disorder contributions to progression of Parkinson’s disease phenotypes
  • Chapter 7
    Reduction of retinal ganglion cell death in mouse models of familial dysautonomia using AAV-mediated gene therapy and splicing modulators
  • Chapter 8
    Tran s c riptome analysis in a humanized mouse model of familial dysautonomia reveals tissue-specific gene e xp r es si on di s r uption in the peripheral nervous system
  • Chapter 9
    Aerobic exercise attenuates dysautonomia, cardiac diastolic dysfunctions, and hemodynamic overload in female mice with atherosclerosis
  • Chapter 10
    Adynamic response to cold pain reflects dysautonomia in type 1 diabetes and polyneuropathy
  • Chapter 11
    Preliminary evaluation of a mindfulness intervention program in women with long COVID dysautonomia symptoms
  • Chapter 12
    Comparison of Dysautonomia Across Species: CurrentKnowledge and Future Research Opportunities
Readership: Students, academics, teachers and other people attending or interested in power conversion.
Alexandra M. Cheney
Department of Chemistry and Biochemistry, Montana State University, Bozeman, MT, USA

Nicholas V. Pinkham
Department of Microbiology and Cell Biology, Montana State University, Bozeman, MT, USA

Young Jin Kim
Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA

and more...
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