Advances in Xenotransplantation

Xenotransplantation (xenos- from the Greek meaning "foreign" or strange), or heterologous transplant, is the transplantation of living cells, tissues or organs from one species to another. Such cells, tissues or organs are called xenografts or xenotransplants. It is contrasted with allotransplantation (from other individual of same species), syngeneic transplantation or isotransplantation (grafts transplanted between two genetically identical individuals of the same species), and autotransplantation (from one part of the body to another in the same person). Xenotransplantation is an artificial method of creating an animal-human chimera, that is, a human with a subset of animal cells. In contrast, an individual where each cell contains genetic material from a human and an animal is called a human–animal hybrid. 

In the present book, ten typical literatures about xenotransplantation published on international authoritative journals were selected to introduce the worldwide newest progress, which contains reviews or original researches on xenotransplantation. We hope this book can demonstrate advances in xenotransplantation as well as give references to the researchers, students and other related people.

Sample Chapter(s)
Preface (282 KB)
Components of the Book:
  • Chapter 1
    Porcine Circoviruses and Xenotransplantation
  • Chapter 2
    Ethical and Societal Issues Occasioned by Xenotransplantation
  • Chapter 3
    Virus Safety of Xenotransplantation
  • Chapter 4
    Advances in Innate Immunity to Overcome Immune Rejection during Xenotransplantation
  • Chapter 5
    Porcine Endogenous Retroviruses in Xenotransplantation—Molecular Aspects
  • Chapter 6
    The Endothelial Glycocalyx in Pig-to-Baboon Cardiac Xenotransplantation—First Insights
  • Chapter 7
    Detection of Pig Cells Harboring Porcine Endogenous Retroviruses in Non-Human Primate Bladder After Renal Xenotransplantation
  • Chapter 8
    Present Advances and Emerging Challenges in Kidney Xenotransplantation
  • Chapter 9
    Human iPSC-Chimera Xenotransplantation and the Non-Identity Problem
  • Chapter 10
    Clinical Islet Xenotransplantation: Development of Isolation Protocol, Anti-Rejection Strategies, and Clinical Outcomes
Readership: Students, academics, teachers and other people attending or interested in Xenotransplantation.
Joachim Denner
Robert Koch Institute, Nordufer 20, 13353 Berlin, Germany

Bernard E. Rollin
Department of Philosophy, Colorado State University, Fort Collins, CO 80523, USA

Martin Bender
Department of Anaesthesiology, University Hospital, LMU Munich, 81377 Munich, Germany

and more...
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