Advances in Leukemia
Leukemia (also spelled leukaemia) is a group of blood cancers that usually begin in the bone marrow and produce high numbers of abnormal blood cells. These blood cells are not fully developed and are called blasts or leukemia cells. Symptoms may include bleeding and bruising, bone pain, fatigue, fever, and an increased risk of infections. These symptoms occur due to a lack of normal blood cells. Diagnosis is typically made by blood tests or bone marrow biopsy.
In the present book, ten typical literatures about leukemia published on international authoritative journals were selected to introduce the worldwide newest progress, which contains reviews or original researches on leukemia. We hope this book can demonstrate advances in leukemia as well as give references to the researchers, students and other related people.
Sample Chapter(s)
Preface (177 KB)
Components of the Book:
  • Chapter 1
    Molecular Mechanisms of Ferroptosis and Updates of Ferroptosis Studies in Cancers and Leukemia
  • Chapter 2
    Clinical Insights into Structure, Regulation, and Targeting of ABL Kinases in Human Leukemia
  • Chapter 3
    Paradigm Shift in the Management of Acute Myeloid Leukemia—Approved Options in 2023
  • Chapter 4
    Targeting FLT3 Mutation in Acute Myeloid Leukemia Current Strategies and Future Directions
  • Chapter 5
    Antineoplastic Activity of Sodium Caseinate in a Cytarabine-Resistant Mouse Acute Myeloid Leukemia Cell Line
  • Chapter 6
    Unveiling the Complexity of KMT2A Rearrangements in Acute Myeloid Leukemias with Optical Genome Mapping
  • Chapter 7
    Molecularly Targeted Therapy in Acute Myeloid Leukemia Current Treatment Landscape and Mechanisms of Response and Resistance
  • Chapter 8
    Current and emerging maintenance strategies after stem cell transplantation in children and adolescents with acute leukemias
  • Chapter 9
    MRD in Acute Leukemias Lessons Learned from Acute Promyelocytic Leukemia
  • Chapter 10
    Unveiling the Role of New Molecules in Acute Myeloid Leukemia Insights into Disease Pathogenesis and Therapeutic Potential
Readership: Students, academics, teachers and other people attending or interested in leukemia.
Naveen Premnath
Division of Hematology and Medical Oncology, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75235, USA

Edgar Ledesma-Martínez
Hematopoiesis and Leukemia Laboratory, Research Unit on Cell Differentiation and Cancer, Faculty of High Studies Zaragoza, National Autonomous University of Mexico, Mexico City 09230, Mexico

Sanam Loghavi
Department of Leukemia and Hematopathology, The University of Texas, MD Anderson, Houston, TX 77030, USA

and more...
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