Advances in Single-Cell Secretion Analysis
Secretion is the movement of material from one point to another, such as a secreted chemical substance from a cell or gland. In contrast, excretion is the removal of certain substances or waste products from a cell or organism. The classical mechanism of cell secretion is via secretory portals at the plasma membrane called porosomes. Porosomes are permanent cup-shaped lipoprotein structures embedded in the cell membrane, where secretory vesicles transiently dock and fuse to release intra-vesicular contents from the cell.
In the present book, ten typical literatures about Single-cell secretion research published on international authoritative journals were selected to introduce the worldwide newest progress, which contains reviews or original researches on Single-cell secretion research. We hope this book can demonstrate advances in Single-cell secretion research as well as give references to the researchers, students and other related people.
Sample Chapter(s)
Preface (44 KB)
Components of the Book:
  • Chapter 1
    A cell-penetrating bispeciffc antibody suppresses hepatitis B virus replication and secretion
  • Chapter 2
    Beta cell speciffc ZnT8 gene deffciency and resulting loss in zinc content signiffcantly improve insulin secretion
  • Chapter 3
    Betagenin ameliorates diabetes by inducing insulin secretion and b-cell proliferation
  • Chapter 4
    Dopamine-mediated autocrine inhibition of insulin secretion
  • Chapter 5
    Identiffcation of cellular signatures associated with chinese hamster ovary cell adaptation for secretion of antibodies
  • Chapter 6
    Impaired ApoB secretion triggers enhanced secretion of ApoE to maintain triglyceride homeostasis in hepatoma cells
  • Chapter 7
    Insights into the relationship between persistent antibody secretion and metabolic programming–A question for single-cell analysis
  • Chapter 8
    Quantitative live-cell imaging of secretion activity reveals dynamic immune responses
  • Chapter 9
    Screening and selection of cellulase-secreting yeast single cells using integrated double emulsion droplet and flow cytometry techniques
  • Chapter 10
    Tacrolimus regulates extracellular vesicle secretion from T cells via autophagy-lysosomal pathway
Readership: Students, academics, teachers and other people attending or interested in Single-Cell Secretion Analysis
Hangrui Liu
School of Engineering, Macquarie University, Sydney, NSW 2109, Australia

Jonathan V. Rocheleau
Institute of Biomedical Engineering, University of Toront o, Toronto, ON M5S 3G9, Canada

Anthony Piro
Department of Physiology, Faculty of Medicine, University of Toro nto, Toronto, Ontario, Canada

and more...
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